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About GERD
Symptoms
Causes
Diagnosis
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CausesWhat Causes GERD? There are two root causes of GERD: those that are chemical in nature and those that stem from anatomical dysfunction. Chemical causes can range from inability of the esophagus to tolerate refluxed materials from the stomach to tissue sensitivities due to natural low acid intolerance, medication use, or ingested substances such as alcohol and tobacco. However, for the majority of sufferers GERD stems from anatomical changes. When a person with normal, healthy anatomy swallows, the valve between the esophagus and the stomach (gastroesophageal valve) opens in order to allow food to pass. This gastroesophageal valve then closes to prevent stomach contents from backwashing or refluxing back up into the esophagus. The normal valve is known as the antireflux barrier and is considered the most important factor in preventing GERD. What Causes the Gastroesophageal Valve to Become Dysfunctional? Any one of these factors, or combination of these factors, can result in disruption of the gastroesophageal valve and abnormal exposure to acid reflux.
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